Pilot testing and evaluation of the CuMP-IA Questionnaire to measure AI integration in precision medicine
Keywords:
Artificial intelligence, Precision medicine, Pilot testing, Healthcare professionals, Measurement instrumentsAbstract
The growing advancement of Artificial Intelligence (AI) in precision medicine has increased the need for valid and reliable instruments that allow researchers to understand how health professionals perceive its integration into clinical practice. For this purpose, a pilot study of the Questionnaire on AI-Based Precision Medicine in Clinical Practice (CuMP-IA) was conducted to evaluate its preliminary applicability and estimate initial indicators of internal consistency. The sample consisted of 42 physicians with teaching experience, who completed the instrument in a virtual format. The pilot study allowed for the examination of item clarity, score behavior, and the reliability of both the overall instrument and its dimensions. The results show an excellent level of global internal consistency (α = 0.925) and two subscales with very high reliability (α ≥ 0.90), supporting their conceptual robustness. However, the remaining dimensions yielded values ranging from low to moderately acceptable (α ≤ 0.689), indicating the need for adjustments before applying the instrument to larger samples.
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Abualigah, L., Alomari, S., Almomani, M., Zitar, R., Saleem, K., Migdady, H., Snásel, V., Smerat, A., & Ezugwu, A. (2025). Artificial intelligence-driven translational medicine: a machine learning framework for predicting disease outcomes and optimizing patient-centric care. Journal of Translational Medicine, 23. https://doi.org/10.1186/s12967-025-06308-6
Ahsan, Z. (2025). Integrating artificial intelligence into medical education: A narrative review. BMC Medical Education. https://link.springer.com/article/10.1186/s12909-025-07744-0
Alowais, S., Alghamdi, S., Alsuhebany, N., Alqahtani, T., Alshaya, A., Almohareb, S., Aldairem, A., Alrashed, M., Saleh, K., Badreldin, H., Yami, M., Harbi, S., & Albekairy, A. (2023). Revolutionizing healthcare: the role of artificial intelligence in clinical practice. BMC Medical Education, 23. https://doi.org/10.1186/s12909-023-04698-z
Bi, W., Hosny, A., Schabath, M., Giger, M., Birkbak, N., Mehrtash, A., Allison, T., Arnaout, O., Abbosh, C., Dunn, I., Mak, R., Tamimi, R., Tempany, C., Swanton, C., Hoffmann, U., Schwartz, L., Gillies, R., Huang, R., & Aerts, H. (2019). Artificial intelligence in cancer imaging: Clinical challenges and applications. Ca, 69, 127 - 157. https://doi.org/10.3322/caac.21552
Boateng, G. O., Neilands, T. B., Frongillo, E. A., Melgar-Quiñonez, H. R., & Young, S. L. (2018).
Best practices for developing and validating scales for health, social, and behavioral research:
A primer. Frontiers in Public Health, 6, 149. https://doi.org/10.3389/fpubh.2018.00149
Borkowski, A., Boyko, O. , & Anne Champeaux, A. (2025). Artificial intelligence in medical education [Preprint]. Preprints. https://www.preprints.org/frontend/manuscript/fc1928f5fb3d7929884061aa5d0e36f8/download_pub
Brew-Sam, N., Parkinson, A., Lueck, C., Brown, E., Brown, K., Bruestle, A., Chisholm, K., Collins, S., Cook, M., Daskalaki, E., Drew, J., Ebbeck, H., Elisha, M., Fanning, V., Henschke, A., Herron, J., Matthews, E., Murugappan, K., Neshev, D., … Desborough, J. (2022). The current understanding of precision medicine and personalised medicine in selected research disciplines: study protocol of a systematic concept analysis. BMJ Open, 12(9), e060326. https://doi.org/10.1136/bmjopen-2021-060326
Busnatu, Ș., Niculescu, A., Bolocan, A., Petrescu, G., Păduraru, D., Nastasa, I., Lupușoru, M., Geantă, M., Andronic, O., Grumezescu, A., & Martins, H. (2022). Clinical Applications of Artificial Intelligence—An Updated Overview. Journal of Clinical Medicine, 11. https://doi.org/10.3390/jcm11082265
Collins, F. S., & Varmus, H. (2015). A new initiative on precision medicine. New England Journal of Medicine, 372(9), 793–795. https://pubmed.ncbi.nlm.nih.gov/25635347/
Copeland, B. J. (2024). MYCIN. Encyclopaedia Britannica. https://www.britannica.com/technology/MYCIN
DeVellis, R. F. (2017). Scale development: Theory and applications (4th ed.). Sage Publications.
Dzau, V. J., & Ginsburg, G. (2016). Realizing the full potential of precision medicine in health and health care. NAM Perspectives. https://pubmed.ncbi.nlm.nih.gov/27669484/
Evans, W., Meslin, E. M., Kai, J., & Qureshi, N. (2024). Precision Medicine—Are We There Yet? A Narrative Review of Precision Medicine’s Applicability in Primary Care. Journal of Personalized Medicine, 14(4), 418. https://doi.org/10.3390/jpm14040418
Ferryman, K., & Pitcan, M. (2018). Precision Medicine? Contemporary Issues and Concerns Primer. Data & Society. https://datasociety.net/wp-content/uploads/2018/02/DataandSociety_What_Is_Precision_Medicine_Primer_2018.pdf
Gazquez-García, J., Sánchez-Bocanegra, C. L., & Sevillano, J. L. (2025). AI in the health sector: Systematic review of key skills for future health professionals. JMIR Medical Education, 11, e58161. https://mededu.jmir.org/2025/1/e58161
Giordano, C., Brennan, M., Mohamed, B., Rashidi, P., Modave, F., & Tighe, P. (2021). Accessing Artificial Intelligence for Clinical Decision-Making. Frontiers in Digital Health, 3. https://doi.org/10.3389/fdgth.2021.645232
Hadweh, P., Niset, A., Salvagno, M., Barajraji, M., Hadwe, S., Taccone, F., & Barrit, S. (2025). Machine Learning and Artificial Intelligence in Intensive Care Medicine: Critical Recalibrations from Rule-Based Systems to Frontier Models. Journal of Clinical Medicine, 14. https://doi.org/10.3390/jcm14124026
Hurtado, C. (2022). Medicina de precisión: conceptos, aplicaciones y proyecciones. Revista Médica Clínica Las Condes, 33(1), 7–16. https://doi.org/10.1016/j.rmclc.2022.01.002
Iqbal, M., Javed, Z., Sadia, H., Qureshi, I., Irshad, A., Ahmed, R., Malik, K., Raza, S., Abbas, A., Pezzani, R., & Sharifi‐Rad, J. (2021). Clinical applications of artificial intelligence and machine learning in cancer diagnosis: looking into the future. Cancer Cell International, 21. https://doi.org/10.1186/s12935-021-01981-1
JASP Team. (2025). JASP (Version 0.18.3) [Computer software]. University of Amsterdam. https://jasp-stats.org/
Jiang F, Jiang Y, Zhi H, Dong Y, Li H, Ma S, et al. (2017). Artificial intelligence in healthcare: past, present and future. Stroke and Vascular Neurology. 2, 230-243. https://doi.org/10.1136/svn-2017-000101
Johanson, G. A., & Brooks, G. P. (2010). Initial scale development: Sample size for pilot studies.
Educational and Psychological Measurement, 70(3), 394–400. https://doi.org/10.1177/0013164409355692
Khalifa, M., & Albadawy, M. (2024). AI in Diagnostic Imaging: Revolutionising Accuracy and Efficiency. Computer Methods and Programs in Biomedicine Update. https://doi.org/10.1016/j.cmpbup.2024.100146
Mello-Thoms, C., & Mello, C. (2023). Clinical applications of artificial intelligence in radiology. The British Journal of Radiology, 96. https://doi.org/10.1259/bjr.20221031
Mosavi, N., & Santos, M. (2024). Enhancing Clinical Decision Support for Precision Medicine: A Data-Driven Approach. Informatics, 11, 68. https://doi.org/10.3390/informatics11030068
National Cancer Institute. (2025). Precision medicine. U.S. Department of Health and Human Services, National Institutes of Health. https://www.cancer.gov/search/results?swKeyword=precision+medicine
National Research Council. (2011). Toward precision medicine: Building a knowledge network for biomedical research and a new taxonomy of disease. National Academies Press. https://www.nationalacademies.org/read/13284
Pallumeera, M., Giang, J., Singh, R., Pracha, N., & Makary, M. (2025). Evolving and Novel Applications of Artificial Intelligence in Cancer Imaging. Cancers, 17. https://doi.org/10.3390/cancers17091510
Srivastav, A., Mishra, M., Lillard, J., & Singh, R. (2025). Transforming Pharmacogenomics and CRISPR Gene Editing with the Power of Artificial Intelligence for Precision Medicine. Pharmaceutics, 17. https://doi.org/10.3390/pharmaceutics17050555
Tekkeşin, A. İ. (2019). Artificial intelligence in healthcare: Past, present and future. Anatolian Journal of Cardiology, 22(Suppl 2), 8–9. https://pubmed.ncbi.nlm.nih.gov/31670713/
Tolentino, R., et al. (2024). Curriculum frameworks and educational programs in AI for medical students, residents, and practicing physicians: Scoping review. JMIR Medical Education, 10, e54793. https://pubmed.ncbi.nlm.nih.gov/39023999/
Topol, E. J. (2019). Deep medicine: How artificial intelligence can make healthcare human again. Basic Books. https://amiif.org/wp-content/uploads/2020/07/10-Disenar-la-medicina-del-futuro.pdf
U.S. Food and Drug Administration. (2013). Paving the Way for Personalized Medicine: FDA’s Role in a New Era of Medical Product Development. U.S. Department of Health and Human Services. http://wayback.archive-it.org/7993/20180125110554/https://www.fda.gov/downloads/ScienceResearch/SpecialTopics/PrecisionMedicine/UCM372421.pdf
Vera, F. (2024). Students’ Perceptions of the Integration of Artificial Intelligence Nursing Education: A Study at a Private Chilean University. Transformar, 5(4), 58–73. https://revistatransformar.cl/index.php/transformar/article/view/148
Vera, F. (2025a). Cuestionario sobre Medicina de Precisión Basada en IA en la Práctica Clínica (CuMP-IA). Red Internacional de Investigadores en Educación (REDIIE). https://rediie.cl/cump-ia/
Vera, F. (2025b). AI-Driven Precision Medicine: Challenges and Opportunities in Training the Next Generation of Physicians. V Congreso Internacional de Tecnología, Aprendizaje y Educación (CITAE 2025), ISSN 2735-6590. https://rediie.cl/wp-content/uploads/AI-Driven-Precision-Medicine....pdf
Wang, J., Zeng, Z., Li, Z., Liu, G., Zhang, S., Luo, C., Hu, S., Wan, S., & Zhao, L. (2025). The clinical application of artificial intelligence in cancer precision treatment. Journal of Translational Medicine, 23. https://doi.org/10.1186/s12967-025-06139-5
Wang, S., Huang, Z., Li, J., Wu, Y., Du, J., & Li, T. (2024). Optimization of diagnosis and treatment of hematological diseases via artificial intelligence. Frontiers in Medicine, 11. https://doi.org/10.3389/fmed.2024.1487234
World Health Organization. (2021). Ethics and governance of artificial intelligence for health. World Health Organization. https://www.who.int/publications/i/item/9789240029200
Yin, J., Ngiam, K., & Teo, H. (2020). Role of Artificial Intelligence Applications in Real-Life Clinical Practice: Systematic Review. Journal of Medical Internet Research, 23. https://doi.org/10.2196/25759









